| Product name | Desmopressin |
| Product No. | 600617 |
| Sequence | Cyclo(Mpr-Tyr-Phe-Gln-Asn-Cys)-Pro-DArg-Gly-NH2 |
| Appearance | White or almost white fluffy powder |
| Solubility | Soluble in water, in ethanol(96%) and in glacial acetic acid |
| Specific Optical Rotation | (-72°to -82°) (C=0.2%, 1% acetic acid,anhydrous and acetic acid free substance) |
| Water | ≤6.0% |
| HPLC | The principal peak in the chromatogram obtained with the test solution is similar in retention time to principal peak in the chromatogram obtained with the reference solution. |
| Amino acid analysis | Asp:0.90-1.10;Glu:0.90-1.10 |
| Pro:0.90-1.10;Gly:0.90-1.10 | |
| Arg:0.90-1.10;Phe:0.90-1.10 | |
| Tyr:0.70-1.05;Cys:0.30-1.05 Lys, Leu and Ile are absent. No more than the traces of the other amino acids are present. | |
| Related substances | Any impurity: NMT 0.5% Total impurity: NMT 2.0% |
| Assay | 95.0%-105.0%(anhydrous and acetic acid free subtance) |
| Acetate acid | 3.0%~8.0% |
| MS | 1129.3 ± 1.0 |
| Bacterial endotoxins | Less than 500EU/mg |
| Storage Condition | In an air tight container, protected from light at temperature 2-8℃. |
Desmopressin Acetate is for the treatment of ①central diabetes insipidus and craniocerebral surgery or surgery caused by temporary diabetes insipidus: after use can reduce urinary excretion, increase urinary osmotic pressure, reduce plasma osmotic pressure, reduce urinary frequency and nocturia (generally on the source of urine Disease is invalid). ② treatment of patients over the age of 5 suffering from nocturnal enuresis. ③For renal urine enrichment function test: to help the identification of renal function, for the diagnosis of different parts of the urinary tract infection is particularly effective. ④ For mild hemophilia and type Ⅰ hemophilia in patients with small surgery can control bleeding or prevent bleeding. ⑤ for uremia, cirrhosis and congenital or drug-induced platelet dysfunction caused by bleeding time is too long and unexplained bleeding, with this product can shorten the bleeding time or return to normal.